Effects of alcohol administered with flibanserin in healthy premenopausal women: A randomized, double-blind, single-dose crossover study

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Effects of alcohol administered with flibanserin in healthy premenopausal women: A randomized, double-blind, single-dose crossover studyIntroduction: Flibanserin is approved in the United States and Canada for the treatment of hypoactive sexual desire disorder in premenopausal women. Aim: The purpose of this trial was to evaluate the safety of concomitant administration of flibanserin with alcohol. Methods:…

Safety and tolerability of evening ethanol consumption and bedtime administration of flibanserin in healthy premenopausal female subjects

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Safety and tolerability of evening ethanol consumption and bedtime administration of flibanserin in healthy premenopausal female subjectsIntroduction: Flibanserin, a treatment for hypoactive sexual desire disorder, carries warnings for increased risk of severe hypotension and syncope when used with alcohol. However, these warnings are not informed by studies that used flibanserin’s recommended bedtime dosing because previous…

Effects of timing of flibanserin administration relative to alcohol intake in healthy premenopausal women: A randomized, double-blind, crossover study

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Effects of timing of flibanserin administration relative to alcohol intake in healthy premenopausal women: A randomized, double-blind, crossover studyIntroduction: Flibanserin is approved in the United States and Canada for the treatment of acquired, generalized, hypoactive sexual desire disorder in premenopausal women. Sedation-related side effects are among the most prevalent adverse events. Although infrequent, hypotension and…